contributor preface partⅠ vectors for gene therapr of cancer 1.retroviral vector design for cancer gene therapy 2.noninfections gene transfer and expression systems for cancer gene therapy 3.parvovirus vectors for the gene therapy of cancer 4.antibody-targeted gene therapy 5.ribozymes in cancer gene therapy 6.the advent of lentiviral vectors:prospects for cancer therapy part Ⅱ immune targetied gene therapy 7.immunologic targets for the gene therapy of cancer part Ⅱa vaccine strategies 8.development of eqitope-specific immunotherapies for human malignancies and premalignant lesions expressing mutated ras genes part Ⅱb dendritic cell-based gene therapy 9.introduction to dendritic cells 10.dna and dendritic cell-based genetic immunization against cancer 11.rna-transfected dendritic cells as immunogens part Ⅱc cytokines and co-factors 12.in situ immune modulation using recombinatnt vaccinia virus vectors:preclinical studies to clinical implementation 13.the use of particle-mediated gene transfer of immunotherapy of cance part Ⅱd genetically modified effector cells for immune-based immunotherapy 14.applications of gene transfer in the adoptive immunotherapy of cancer 15.update on the use of genetically modified hematoppietic stem cells for cancer therapy part Ⅲ oncogene-targeted gene therapy 16.clinical applications of tumor-suppressor gene therapy 17.cancer gene therapy with tumor supperssor genes involved in cell-cycle control 18.cancer gene therapy with the p53 tumor suppressor gene 19.antisense downregulation of the apoptosis-related bcl-2and bcl-xl proteins:a new approach to cancer therapy 20.gene therpy for chronic myelogenous leukemia part Ⅳ manulation of drug resistance mechanisms by gene therary …… part Ⅴ anti-aniogenesis and pro-aportotic gene therapy part Ⅵ prodrug activation strategies for gene therapy of cancer index