Chapter 1 Introduction Chapter 2 Chromosomal Basis of Heredity Chapter 3 The Human Genome: Structure and Function of Genes and Chromosomes Chapter 4 Tools of Human Molecular Genetics Chapter 5 Patterns of Single-Gene Inheritance Chapter 6 Genetic Variation in Individuals:Mutation and Polymorphism Chapter 7 Genetic Variation in Populations Chapter 8 Gene Mapping and the Human Genome Project Chapter 9 Principles of Clinical Cytogenetics Chapter 10 Clinical Cytogenetics: Disorders of the Autosomes and the Sex Chromosomes Chapter 11 Principles of Molecular Disease:Lessons from the Hemoglobinopathies Chapter 12 The Molecular and Biochemical Basis of Genetic Disease Chapter 13 The Treatment of Genetic Disease Chapter 14 Genetics of the Immune System Chapter 15 Genetics of Disorders with Complex Inheritance Chapter 16 Genetics and Cancer Chapter 17 Genetic Aspects of Development Chapter 18 Prenatal Diagnosis Chapter 19 Genetic Counseling and Risk Assessment Chapter 20 Genetics and Society Glossary Answers to Problems Index